Search DePuy Synthes




About this product

Division: CMF
Category: Biomaterials

chronOS™ Granules and Preforms System are widely used as osteoconductive bone graft substitutes. Perfusion of the highly porous β-tricalcium phosphate material with autologous bone marrow introduces blood cells, growth factors, and osteoprogenitor cells; thus, accelerates and enhances osteointegration.

For easy handling, chronOS preforms are available prepackaged in special Vivify perfusion pouch that allow that allow for simple perfusion with bone marrow aspirate or blood.


Intended Use

chronOS Granules and Preforms System should be used as bone void fillers or augmentation material in zones requiring cancellous rather than cortical bone. This includes the filling of bone defects after trauma, reconstruction or correction in non-load-bearing indications only1.

1For the intended use and a complete set of indications, contraindications, warnings and precautions, see the instructions for use (IFU).

Features & Benefits


  Features Benefits
  Autologous bone marrow   Osteopromotion: accelerated and enhanced osteointegration 
  Vacuum perfusion pouch Efficient impregnation of chronOS performs with bone marrow 
  Intra-operative aspiration technique   Time and cost saving procedure
  Minimally invasive procedure   Reduced morbidity 
  Synthetic origin of chronOS   Avoids potential problems common for grafting methods 
  Optimized porosity of chronOS   Enhanced bone ingrowth and vascularization 
Please refer to the surgical technique guide or package inserts if included for a complete list of indications, contraindications, precautions and warnings. For further information on DePuy Synthes Products, please contact your local DePuy Synthes Representative .
Back To Top