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About this product

Division: Biomaterials

chronOS™ Inject Bone Void Filler is a synthetic, osteoconductive calcium phosphate bone substitute. The material is injectable, osteoconductive, and resorbable. Irregular bone defects can be completely filled with chronOS Inject Bone Void Filler using a minimally invasive technique. chronOS Inject Bone Void Filler hardens without an exothermal reaction. The hardening process also proceeds in a humid environment. chronOS Inject Bone Void Filler is remodeled into host bone within 6 to 18 months.


Intended Use

chronOS Inject Bone Void Filler is intended to be used as bone void filler or augmentation material where cancellous or cortico-cancellous bone should be replaced. This includes the filling of bone defects in the upper and lower extremities and pelvis in non-load bearing indications only1.

1 For the intended use and a complete set of indications, contraindications, warnings and precautions, see the instructions for use (IFU).

Features & Benefits


  Features Benefits
  Injectable material  Minimally invasive treatment 
  Biphasic material structure; Bone-like substance   Remodels in 6 – 18 months 
  Not exothermic  Preserves soft tissue and blood supply 
  Synthetic origin of chronOS Inject Bone Void Filler  Avoid problems with traditional grafting methods; Consistent quality; Sufficient quantity 
  Manual mixing   Easy to use 
Please refer to the surgical technique guide or package inserts if included for a complete list of indications, contraindications, precautions and warnings. For further information on DePuy Synthes Products, please contact your local DePuy Synthes Representative .
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