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New Knee System Designed to Address Unmet Needs and Deliver High Level of Stability and Optimum Range of Motion

Leeds, United Kingdom – 13 September 2013 – Today DePuy Synthes Joint Reconstruction, a global leader in devices for joint replacement, introduces its latest innovation in total knee replacement— the ATTUNETM Knee System. Created as a result of more than six years of extensive research, the ATTUNE Knee is an advancement in knee replacement that addresses a significant unmet need for patients, surgeons and providers. It is designed to provide better range of motion and improve the unstable feeling some patients experience during everyday activities.

Studies have shown that 10 to 20 percent of patients are not completely satisfied with their knee replacement  1  and everyday tasks, such as stair descent and bending, are challenging. Further, research shows that 32 percent of patients are unable to kneel because of discomfort in the knee after knee replacement surgery. 2  This reduced mobility can seriously affect a patient’s quality of life.

“The ATTUNE Knee System is an innovative step forward in total knee replacement and has the potential to greatly benefit patients who are struggling with knee pain,” said Mr. Peter James, Consultant Orthopaedic Surgeon, Nottingham City Hospital and ATTUNE Knee System Design Team Surgeon**, “By providing patients with the freedom of movement and reassurance of stability, surgeons like myself have an innovative new solution to offer our patients.”

Through a research collaboration with multiple institutions, including University College Dublinin Ireland, DePuy Synthes Joint Reconstruction evaluated contemporary knee designs to assess how sizing and implant geometry aids in maintaining stability through patient’s daily activities.

Additional research with a team of surgeons and industry experts from around the world led to several proprietary technologies for the ATTUNE Knee. This research included x-rays of patient movement, cadaver knees and computer simulations. The resulting proprietary technologies include:

  • ATTUNE GRADIUS™ Curve: A gradually reducing radius that provides optimum conformity throughout the range of motion and is designed to achieve anterior/posterior stability
  • SOFCAM™ Contact: An S-curve design that provides a smooth engagement for stability through flexion, while reducing stresses placed on the implant
  • LOGICLOCK™ Tibial Base: A locking design that provides the architecture to optimise kinematics while reducing wear to the lowest reported levels in the industry.3 As a result, surgeons do not have to compromise on component size, picking the optimum size and fit for each patient from the range of sizing options
  • GLIDERIGHT™ Articulation: A design to accommodate patient variation and soft tissue interaction, while optimising patella tracking

“As part of a European-wide rollout, the ATTUNE Knee System will now be comercially available across multiple markets in Europe, providing surgeons and patients with access to the latest knee replacement technologies. The ATTUNE Knee is the result of the largest research and development project in DePuy Synthes history,” said Gary Lancaster, EMEA Marketing Director, DePuy Synthes. 

As part of the ATTUNEKnee research and development, DePuy Synthes Joint Reconstruction also developed INTUITION™ Instruments in collaboration with the Royal College of Art in the UK, which are compatible with the ATTUNE Knee and are designed to help the surgeon deliver stability in motion. The INTUITION Instrumentsenable surgeons to provide more efficient patient care through the following features:

  • Novel use of composite materials in orthopaedic instruments
  • Single-layer instrument cases that are lightweight with fewer instruments, reducing weight by 51 percent as compared to previously available instruments. The instruments also minimise the number of cases in the operating room (OR) while maintaining durability
  • Designed clarity through the use of colour coding and clear markings, potentially reducing OR surgical errors
  • Reduction of surgical steps to help provide set-up efficiency


Notes to Editors

*DePuy Synthes Joint Reconstructionis a division of DePuy Orthopaedics, Inc.
**Consultant to DePuy Synthes Joint Reconstruction

Important Safety Information

The performance of hip or knee replacements depends on a patient’s age, weight, activity level and other factors. There are potential risks and recovery takes time. People with conditions limiting rehabilitation should not have these surgeries. Only an orthopaedic surgeon can determine if hip or knee replacement is necessary based on an individual patient's condition.


About DePuy Synthes Joint Reconstruction

DePuy Synthes Joint Reconstruction, a global leader in hip, knee and shoulder replacement, is part of DePuy Synthes Companies of Johnson & Johnson, the largest provider of orthopaedic and neurological solutions in the world.

This press release contains "forward-looking statements" as defined in the Private Securities Litigation Reform Act of 1995.  The reader is cautioned not to rely on these forward-looking statements. These statements are based on current expectations of future events.  If underlying assumptions prove inaccurate or unknown risks or uncertainties materialize, actual results could vary materially from the expectations and projections of DePuy Orthopaedics, Inc. and/or Johnson & Johnson.  Risks and uncertainties include, but are not limited to, general industry conditions and competition; economic factors, such as interest rate and currency exchange rate fluctuations; technological advances, new products and patents attained by competitors; challenges inherent in new product development, including obtaining regulatory approvals; challenges to patents; changes in behavior and spending patterns or financial distress of purchasers of health care products and services; changes to governmental laws and regulations and domestic and foreign health care reforms; trends toward health care cost containment; and increased scrutiny of the health care industry by government agencies.  A further list and description of these risks, uncertainties and other factors can be found in Exhibit 99 of Johnson & Johnson’s Annual Report on Form 10-K for the fiscal year ended December 30, 2012.  Copies of this Form 10-K, as well as subsequent filings, are available online at www.sec.gov , www.jnj.com or on request from Johnson & Johnson.  Neither DePuy Orthopaedics, Inc. nor Johnson & Johnson undertake to update any forward-looking statements as a result of new information or future events or developments.



Jenny Skilbeck
DePuy Synthes
Tel: +44 (0) 113 387 7862
Email:  jskilbec@its.jnj.com


1. Baker PN, van der Meulen JH, Lewsey J, Gregg PJ. The Role of Pain and Function in Determining Patient Satisfaction After Total Knee Replacement. JBJS-Br. 2007; 89-B(7): 893-900.
2. S.H. Palmer. The Bone and Joint Journal. Ability to kneel after total knee replacement.
3. Leisinger S, Hazebrouck S, Deffenbaugh D, Heldreth M. Advanced Fixed Bearing TKA Locking Mechanism Minimizes Backside Micromotion. International Society for Technology in Arthroplasty (ISTA) Annual Meeting. 2011.


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