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Proving The Promise

Proving the promise


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The ATTUNE Knee is a total primary knee system designed with the goal of addressing the clinical needs of patients, surgeons and hospital providers around the world. Extensive research and science has been included in the design to help improve functional outcomes for patients, performance for surgeons, and efficiency for providers.

The ATTUNE Knee is one of the largest research and development projects in the history of DePuy Synthes Companies and combines the latest in design, kinematics, engineering and materials to deliver stability and motion.

To find out more about Proving The Promise watch our overview film

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To design a total knee system with the goal of addressing unmet clinical needs, helping improve functional outcomes and positively impact patient satisfaction.


Developing a new system

DePuy Synthes is world renowned for its knowledge and development of successful knee replacement systems. Some of the iconic DePuy Synthes primary knees include the SIGMA® Knee System and the LCS™ Knee System. Total knee replacement surgery can be a highly successful procedure. However, it is also a complex procedure. Surgeons are faced with varying patient anatomies and difficult intra-operative decisions each time they enter the operating room (OR). At the same time, patients seek to return to the normal and active lifestyle they enjoyed prior to the onset of their joint disease.

Unfortunately, total knee patients are not always satisfied with their outcome and report differing levels of satisfaction following surgery. It is the goal of DePuy Synthes Companies to design total knee systems that work with the surgeon to positively impact patient satisfaction.

Learn more about DePuy Synthes research and development history and why DePuy Synthes developed the ATTUNE Knee System.

  1. 1. Association of American Retired Persons (AARP). Joint Replacement Surgery Patient Survey. 2007 September. Conducted in Boston, MA; September 6-8, 2007.
  2. 2. Baker PN, van der Meulen JH, Lewsey J, Gregg PJ. The Role of Pain and Function in Determining Patient Satisfaction After Total Knee Replacement. JBJS-Br. 2007; 89-B(7): 893-900


Extensive research and science combining the latest in design kinematics, engineering and materials has been incorporated in the ATTUNE Knee System to deliver a high level of stability and motion.


Innovative. Comprehensive. Integrated.

To better understand what factors may lead to improved patient satisfaction, Depuy Synthes embarked on one of the largest research and development project in its history. DePuy Synthes clinical heritage in knee replacement design is recognized in the industry. With this foundation in clinically proven design principles, the design team re-examined every aspect of knee implant and instrument design. A world class surgeon team was assembled and working relationships with leading research facilities were established to study areas such as kinematics, anthropometrics, polyethylene wear, and instrument design.

The following goals were established:

  • Improve function through motion and stability
  • Improve patient fit
  • Improve patello-femoral function
  • Improve design and materials for implant durability
  • Advance surgical process for implant positioning OR efficiency


Attune Gradius Curve

The patented ATTUNE GRADIUS Curve is designed with a gradually reducing femoral radius. This curve creates a smooth transition during knee bending and produces high stability of the knee by minimizing unnatural sliding of the femur on the tibia.

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SOFCAM Contact

For the Posterior Stabilized design, the interaction between the cam and spine, the articular surface geometry, and the collateral ligaments is complex and essential to the function of the knee in deep flexion. The proprietary s-curve design of the SOFCAM Contact provides a smooth engagement for gradual femoral rollback and stability in flexion, while reducing the forces transferred to the tibial spine.4

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Differentiated to current offerings, surgeons are able to match the femoral size to the insert size every time to achieve the highest conformity and optimized stability in early flexion. 5 The LOGICLOCK Tibial Base allows surgeons to use a tibial base that can be upsized or downsized two sizes versus the insert.

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GLIDERIGHT Articulation

The patello-femoral interaction is one of the more challenging aspects of total knee arthroplasty. 10 The GLIDERIGHT Articulation encompasses a trochlear groove designed to accommodate patient variation and soft tissue interaction, and patella components designed to optimize patella tracking while maintaining bone coverage.

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Clary CW. Wright A Kamoso Maletsky L The effect of patella medialization on patellofemoral kinematics after Total Knee replacements. Journal of Biomechanics. July 2012. 45 (Supplement 1). S374



To provide implant sizes that were reflective of the global patient population, DePuy Synthes Companies collaborated with University College Dublin to conduct extensive anthropometric research. The ATTUNE Knee Femoral Sizing Line was created to accommodate the global patient population and avoid mediolateral overhang.

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The INTUITION Instruments were developed to deliver efficiencies for all stakeholders and an intuitive surgical process. Advanced composite materials and modular designs allow lighter instruments, less trials, and less instrument trays while providing intraoperative flexibility for the surgeon. 11

These innovative instruments work with the advancements in the implant design to help balance the soft tissues and precisely control the implant position and fit for each patient.

Precise Control Animation
Efficient Path Animation
Design Clarity Animation
  1. 3 Clary, C. W., Fitzpatrick, C. K., Maletsky, L. P., & Rullkoetter, P. J. (2012). Improving dynamic mid-stance stability: an experimental and finite element study. Orthopaedic Research Society, 58th Annual Meeting, Poster Number1044, San Francisco, CA.
  2. 4 Fitzpatrick, C. K., Clary, C. W., & Rullkoetter, P. J. (2012). Post-cam engagement during dynamic activity with current posterior stabilized TKR. 18th European Society of Biomechanics, Presentation Number 1700, Lisbon, Portugal
  3. 5 Fitzpatrick, C. K., Clary, C. W., & Rullkoetter, P. J. (2012). The influence of design on TKR mechanics during activities of daily living. Orthopaedic Research Society, 58th Annual Meeting, Poster Number 2034, San Francisco, CA
  4. 6 Zimmer, Inc. (2012). Persona: The Personalized Knee System Product Profiler. Warsaw, IN
  5. 7 Stryker, Inc. (2004). Triathlon Knee System Product Catalog. Mawhaw, NJ
  6. 8 Biomet, Inc. (2007). Vanguard Knee System, Design Rationale. Warsaw, IN
  7. 9 Smith & Nephew, Inc. (2013). Journey II Surgical Technique. Memphis, TN
  8. 10 Amis, A. A., Senavongse, W., Bull, A. M. J. (2006). Patellofemoral kinematics during knee flexion-extension: an in vitro study. Journal of Orthopaedic Research, 24, 2201-2211
  9. 11 DePuy Synthes Companies. (Oct 2012). Data on File: ATTUNE Reduction in Tray Weight. Warsaw, IN


There are multiple global, comprehensive studies, both company and independent initiated, designed to provide evidence in support of the ATTUNE Knee System.



In Vivo Evidence

Analysis of Total Knee Replacement using the ATTUNE Knee System in the National Joint Registry for England, Wales, Northern Ireland and the Isle of Man.

According to the UK NJR 3 year paper and study referenced in the link below, at 3 years the ATTUNE Knee System performs as well as the SIGMA Knee System and as well as the class of cemented Total Knee Replacement.

  • 98.70% survivorship at 3 years for the ATTUNE Knee System
  • 5,388 implantations with only 18 revision procedures (11 excluding infection)


DePuy Synthes value based healthcare team aim to improve clinical outcomes and patient experiences whilst improving efficiencies.


DePuy Synthes Advantage™

Our mission is to provide Hospitals with value-based healthcare solutions that augments the provision of best-in-class products, helping customers achieve the goals of the Triple Aim performance – sustainably.

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eSIMS Advanced Inventory Management Solution

Is designed to aid in the management and ordering of DePuy Synthes inventory by utilising the barcodes printed on sterile and non-sterile product packaging.

The eSIMS software is designed to improve efficiencies and optimise the supply chain by greatly reducing time, costs, resources, and errors throughout the inventory management and procurement process, helping to create the ‘perfect order’.

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Care4Today® Orthopedic Solutions is an end-to-end technology-enabled patient pathway program build on the principles of enhanced recovery. The solution is built around a modular approach: Audit, Change Management, Patient Education, Digital Patient Engagement, and PROMs, where we design the best program to meet your needs elective hip and knee procedures.

Through this program we aim to deliver improved clinical outcomes, improved patient satisfaction and experience, and reduced costs.

Care4Today Theatre Efficiency Programme

Real Life Tested

A Hip and Knee Replacement education and awareness site for Patients and their Family Doctors.



Johnson and Johnson Medical Devices and DePuy Synthes Companies share a common vision – providing the technologies and surgical training needed to improve the lives of patients all around the world. The best patient outcomes are achieved when surgeons have the right products along with the knowledge to use them safely and effectively. That’s why we’ve developed extensive professional education programs which have made us one of the leaders in surgeon training.


Learn Smarter. Join 1000’s of surgeons who develop their knowledge and skills on It's free, and you will gain access to a personalized library of high-quality surgical videos, presentations, case studies and webcasts from some of the world's leading surgeons.


Visitation Centres (VCs) are an established part of the DePuy Synthes Professional Education Pathway for Healthcare Professionals (HCPs). They provide the respective HCP with an opportunity to visit a recognized Key Opinion Leader (KOL) at their practice/centre of excellence in small groups of 2 – 4 HCPs. The objective of each VC is to enable the visiting HCP to have a better understanding of a specific technique/procedure that may have previously been introduced at a DePuy Synthes course or on-line at


For additional information about any of the DePuy Synthes events please contact your local DePuy Synthes representative


There are multiple global, comprehensive studies, both company and independent initiated, designed to provide evidence in support of the ATTUNE Knee System.


DePuy Synthes Companies Announces New ATTUNE® Revision Fixed Bearing Tibial Base and Cemented Stem for Primary and Revision Surgeries

Vienna, AT –  1 June 2017 – Today DePuy Synthes, part of the Johnson & Johnson Family of Companies, announced the Europe, Middle East and Africa launch of the first ATTUNE® Knee revision options, the ATTUNE Revision Fixed Bearing Tibial Base and the 14x50 mm Cemented Stem.

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2017 News Articles

ATTUNE® Knee System Four-Year Revision Rate is Lower Than Total Knee Class, According to New & Independent Joint Registry Data

Vienna, AT –  31 May 2017 – DePuy Synthes, part of the Johnson & Johnson Family of Companies, today announced new ATTUNE® Knee implant survivorship data based on an Implant Summary Report obtained from the National Joint Registry for England, Wales, Northern Ireland and the Isle of Man (NJR).

National Joint Registry releases its Implant Summary Report for primary knee implants.

London, UK – 27 April 2017 – Today, the National Joint Registry released its Implant Summary Report for primary knee implants.

New report demonstrates the clinical and economic value of the Attune® Knee System in today’s value-based environment

London, UK – 20 April 2017 – Today, DePuy Synthes, part of the Johnson & Johnson Family of Companies, released the report, “Improving the Value of Primary Total Knee Arthroplasty: the ATTUNE® Knee System,” that analyzes the ATTUNE Knee’s current clinical and economic data.

2016 News Articles

Latest Australian Joint Registry Data Confirm Positive Early Results For the ATTUNE® Knee System.

Solothurn, Switzerland - 19 December 2016, DePuy Synthes, part of the Johnson & Johnson Family of Companies, today announced that implant survivorship [Read more...]

Latest UK joint registry data confirms positive early results for the DePuy Synthes ATTUNE® Knee System.

Solothurn, Switzerland – 29 November 2016, DePuy Synthes Joint Reconstruction, today announced the latest clinical evidence of the performance of the [Read more...]

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